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Maternal treatment with short-chain fatty acids modulates the intestinal microbiota and immunity and ameliorates type 1 diabetes in the offspring
We recently hypothesized that the intestinal microbiota and the innate immune system play key roles in the mechanism of Kilham Rat Virus-induced type 1 diabetes in the LEW1.WR1 rat. We used this animal model to test the hypothesis that maternal therapy with short-chain fatty acids can modulate the i...
Autores principales: | Needell, James C., Ir, Diana, Robertson, Charles E., Kroehl, Miranda E., Frank, Daniel N., Zipris, Danny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590848/ https://www.ncbi.nlm.nih.gov/pubmed/28886045 http://dx.doi.org/10.1371/journal.pone.0183786 |
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