Biophysical analysis of the effect of chemical modification by 4-oxononenal on the structure, stability, and function of binding immunoglobulin protein (BiP)

Binding immunoglobulin protein (BiP) is a molecular chaperone important for the folding of numerous proteins, which include millions of immunoglobulins in human body. It also plays a key role in the unfolded protein response (UPR) in the endoplasmic reticulum. Free radical generation is a common phe...

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Detalles Bibliográficos
Autores principales: Shah, Dinen D., Singh, Surinder M., Dzieciatkowska, Monika, Mallela, Krishna M. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590874/
https://www.ncbi.nlm.nih.gov/pubmed/28886061
http://dx.doi.org/10.1371/journal.pone.0183975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590874/
https://www.ncbi.nlm.nih.gov/pubmed/28886061
http://dx.doi.org/10.1371/journal.pone.0183975

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