Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes

Burn patients suffer from immunological dysfunction for which there are currently no successful interventions. Similar to previous observations, we find that burn shock patients (≥15% Total Burn Surface Area (TBSA) injury) have elevated levels of the innate immune cytokines Interleukin-6 (IL-6) and...

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Detalles Bibliográficos
Autores principales: Eitas, Timothy K., Stepp, Wesley, Sjeklocha, Lucas, Long, Clayton, Riley, Caitlin, Callahan, James, Sanchez, Yolanda, Gough, Peter, Knowlin, Laquanda, van Duin, David, Ortiz-Pujols, Shiara, Jones, Samuel, Maile, Robert, Hong, Zhi, Berger, Scott, Cairns, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590883/
https://www.ncbi.nlm.nih.gov/pubmed/28886135
http://dx.doi.org/10.1371/journal.pone.0184164

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590883/
https://www.ncbi.nlm.nih.gov/pubmed/28886135
http://dx.doi.org/10.1371/journal.pone.0184164

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