Cargando…

Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes

Burn patients suffer from immunological dysfunction for which there are currently no successful interventions. Similar to previous observations, we find that burn shock patients (≥15% Total Burn Surface Area (TBSA) injury) have elevated levels of the innate immune cytokines Interleukin-6 (IL-6) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Eitas, Timothy K., Stepp, Wesley, Sjeklocha, Lucas, Long, Clayton, Riley, Caitlin, Callahan, James, Sanchez, Yolanda, Gough, Peter, Knowlin, Laquanda, van Duin, David, Ortiz-Pujols, Shiara, Jones, Samuel, Maile, Robert, Hong, Zhi, Berger, Scott, Cairns, Bruce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590883/ https://www.ncbi.nlm.nih.gov/pubmed/28886135 http://dx.doi.org/10.1371/journal.pone.0184164

Ejemplares similares

Correction: Differential regulation of innate immune cytokine production through pharmacological activation of Nuclear Factor-Erythroid-2-Related Factor 2 (NRF2) in burn patient immune cells and monocytes
por: Eitas, Timothy K., et al.
Publicado: (2017)

Nrf2 in TIME: The Emerging Role of Nuclear Factor Erythroid 2-Related Factor 2 in the Tumor Immune Microenvironment
por: Feng, Jialin, et al.
Publicado: (2023)

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction()
por: Chepelev, Nikolai L., et al.
Publicado: (2013)

Clinicopathological significance of nuclear factor (erythroid-2)-related factor 2 (Nrf2) expression in gastric cancer
por: Kawasaki, Yota, et al.
Publicado: (2015)

Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Mitochondrial Dynamics/Mitophagy in Neurological Diseases
por: Kang, Tae-Cheon
Publicado: (2020)

The Potential Role of Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) in Glaucoma: A Review
por: Wang, Mingxuan, et al.
Publicado: (2020)

PARP2 poly(ADP-ribosyl)ates nuclear factor erythroid 2-related factor 2 (NRF2) affecting NRF2 subcellular localization
por: Jankó, Laura, et al.
Publicado: (2023)

Nuclear factor erythroid 2–related factor 2 (Nrf2) deficiency causes age-dependent progression of female osteoporosis
por: Kubo, Yusuke, et al.
Publicado: (2022)

Impact of Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocellular Carcinoma: Cancer Metabolism and Immune Status
por: Iseda, Norifumi, et al.
Publicado: (2021)

Loss of Transcription Factor Nuclear Factor-Erythroid 2 (NF-E2) p45-related Factor-2 (Nrf2) Leads to Dysregulation of Immune Functions, Redox Homeostasis, and Intracellular Signaling in Dendritic Cells
por: Yeang, Han Xian Aw, et al.
Publicado: (2012)

The Effects of Nuclear Factor Erythroid 2 (NFE2)-Related Factor 2 (Nrf2) Activation in Preclinical Models of Peripheral Neuropathic Pain
por: Basu, Paramita, et al.
Publicado: (2022)

Near-peer mentoring and virtual reality for adult basic life support education in high school students
por: Knowlin, Laquanda T., et al.
Publicado: (2023)

Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases
por: Francisqueti-Ferron, Fabiane Valentini, et al.
Publicado: (2019)

Inhibition of nuclear factor-erythroid 2–related factor (Nrf2) by caveolin-1 promotes stress-induced premature senescence
por: Volonte, Daniela, et al.
Publicado: (2013)

Oxidative Stress in Arterial Hypertension (HTN): The Nuclear Factor Erythroid Factor 2-Related Factor 2 (Nrf2) Pathway, Implications and Future Perspectives
por: Tanase, Daniela Maria, et al.
Publicado: (2022)

Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Mediates Neuroprotection in Traumatic Brain Injury at Least in Part by Inactivating Microglia
por: Wu, Gang, et al.
Publicado: (2016)

Strange Bedfellows: Nuclear Factor, Erythroid 2-Like 2 (Nrf2) and Hypoxia-Inducible Factor 1 (HIF-1) in Tumor Hypoxia
por: Toth, Rachel K., et al.
Publicado: (2017)

Safety and efficacy of aged garlic extract in dogs: upregulation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway and Nrf2-regulated phase II antioxidant enzymes
por: Yamato, Osamu, et al.
Publicado: (2018)

Hydrogen Sulfide Levels and Nuclear Factor-Erythroid 2-Related Factor 2 (NRF2) Activity Are Attenuated in the Setting of Critical Limb Ischemia (CLI)
por: Islam, Kazi N, et al.
Publicado: (2015)

Beneficial effects of Oltipraz, nuclear factor - erythroid – 2 - related factor 2 (Nrf2), on renal damage in unilateral ureteral obstruction rat model
por: Polat, Emre Can, et al.
Publicado: (2018)

The effect of dietary phytochemicals on nuclear factor erythroid 2-related factor 2 (Nrf2) activation: a systematic review of human intervention trials
por: Clifford, Tom, et al.
Publicado: (2021)

Inhibition of miR-448-3p Attenuates Cerebral Ischemic Injury by Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2)
por: Xu, Min, et al.
Publicado: (2021)

Prognostic Value and Immune Infiltration Analysis of Nuclear Factor Erythroid-2 Family Members in Ovarian Cancer
por: Dou, Rui, et al.
Publicado: (2022)

Molecular Evolution of the Nuclear Factor (Erythroid-Derived 2)-Like 2 Gene Nrf2 in Old World Fruit Bats (Chiroptera: Pteropodidae)
por: Yin, Qiuyuan, et al.
Publicado: (2016)

The nuclear factor (erythroid-derived 2)-like 2 (Nrf2) activator dh404 protects against diabetes-induced endothelial dysfunction
por: Sharma, Arpeeta, et al.
Publicado: (2017)

Nitrite Therapy Ameliorates Myocardial Dysfunction via H(2)S and Nuclear Factor‐Erythroid 2‐Related Factor 2 (Nrf2)‐Dependent Signaling in Chronic Heart Failure
por: Donnarumma, Erminia, et al.
Publicado: (2016)

Melatonin Upregulates Nuclear Factor Erythroid-2 Related Factor 2 (Nrf2) and Mediates Mitophagy to Protect Against Early Brain Injury After Subarachnoid Hemorrhage
por: Sun, Bin, et al.
Publicado: (2018)

Role of Nuclear Factor Erythroid 2 (Nrf2) in the Recovery of Long COVID-19 Using Natural Antioxidants: A Systematic Review
por: Muchtaridi, Muchtaridi, et al.
Publicado: (2022)

Role of Nuclear Factor Erythroid 2-Related Factor 2 in Diabetic Nephropathy
por: Cui, Wenpeng, et al.
Publicado: (2017)

Nuclear Factor Erythroid 2-Related Factor 2 in Regulating Cancer Metabolism
por: Smolková, Katarína, et al.
Publicado: (2020)

Abstract: Even Better Than the Real Thing? The Use of Xenografting in Pediatric Patients with Scald Injury -- A Single-Institution, 10-Year Review
por: Hermiz, Steven J., et al.
Publicado: (2016)

Abstract: In a Little While: Anticipating Changes in Bundled Payments for the Treatment of Patients with Acute, Life-threatening Dermatologic Emergencies, Through Prevention of Healthcare Associated Infections.
por: Hermiz, Steven J., et al.
Publicado: (2016)

Sestrin2 Regulates Endoplasmic Reticulum Stress-Dependent Ferroptosis to Engage Pulmonary Fibrosis by Nuclear Factor Erythroid 2-Related Factor 2/Activating Transcription Factor 4 (NRF2/ATF4)
por: Dong, Zhaoxing, et al.
Publicado: (2023)

Nuclear Factor-erythroid 2 (NF-E2) p45-related Factor-2 (Nrf2) Modulates Dendritic Cell Immune Function through Regulation of p38 MAPK-cAMP-responsive Element Binding Protein/Activating Transcription Factor 1 Signaling
por: Al-Huseini, Laith M. A., et al.
Publicado: (2013)

The Taming of Nuclear Factor Erythroid-2-Related Factor-2 (Nrf2) Deglycation by Fructosamine-3-Kinase (FN3K)-Inhibitors-A Novel Strategy to Combat Cancers
por: Beeraka, Narasimha M., et al.
Publicado: (2021)

Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function
por: Chen, Zhijiang, et al.
Publicado: (2022)

Immune‐Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2–Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia–Reperfusion Injury
por: Yi, Zhongjie, et al.
Publicado: (2020)

Immune-responsive gene 1/itaconate activates nuclear factor erythroid 2-related factor 2 in microglia to protect against spinal cord injury in mice
por: Ni, Libin, et al.
Publicado: (2022)

Erratum - Transcription factor nuclear factor erythroid 2 p45-related factor 2 (NRF2) ameliorates sepsis-associated acute kidney injury by maintaining mitochondrial homeostasis and improving the mitochondrial function
por: Chen, Zhijiang, et al.
Publicado: (2023)

The role of nuclear factor erythroid-2-related factor 2 expression in radiocontrast-induced nephropathy
por: Kim, Ji Eun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_7s9f3rjudvuntt15mof7t461so