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Orexin A affects HepG2 human hepatocellular carcinoma cells glucose metabolism via HIF-1α-dependent and -independent mechanism

Orexins are hypothalamic neuropeptides that regulate feeding, reward, wakefulness and energy homeostasis. The present study sought to characterize the involvement of orexin A in glucose metabolism in HepG2 human hepatocellular carcinoma cells, and investigated the role of hypoxia-inducible factor-1α...

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Detalles Bibliográficos
Autores principales: Wan, Xing, Liu, Yuanyuan, Zhao, Yuyan, Sun, Xiaoqi, Fan, Dongxiao, Guo, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590901/
https://www.ncbi.nlm.nih.gov/pubmed/28886081
http://dx.doi.org/10.1371/journal.pone.0184213