Haloperidol induces pharmacoepigenetic response by modulating miRNA expression, global DNA methylation and expression profiles of methylation maintenance genes and genes involved in neurotransmission in neuronal cells

INTRODUCTION: Haloperidol has been extensively used in various psychiatric conditions. It has also been reported to induce severe side effects. We aimed to evaluate whether haloperidol can influence host methylome, and if so what are the possible mechanisms for it in neuronal cells. Impact on host m...

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Detalles Bibliográficos
Autores principales: Swathy, Babu, Banerjee, Moinak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590913/
https://www.ncbi.nlm.nih.gov/pubmed/28886082
http://dx.doi.org/10.1371/journal.pone.0184209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590913/
https://www.ncbi.nlm.nih.gov/pubmed/28886082
http://dx.doi.org/10.1371/journal.pone.0184209

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