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A study of the structural properties of sites modified by the O-linked 6-N-acetylglucosamine transferase

Protein O-GlcNAcylation (O-GlcNAc) is an essential post-translational modification (PTM) in higher eukaryotes. The O-linked β-N-acetylglucosamine transferase (OGT), targets specific Serines and Threonines (S/T) in intracellular proteins. However, unlike phosphorylation, fewer than 25% of known O-Glc...

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Detalles Bibliográficos
Autores principales: Britto-Borges, Thiago, Barton, Geoffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590929/
https://www.ncbi.nlm.nih.gov/pubmed/28886091
http://dx.doi.org/10.1371/journal.pone.0184405