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Directional migration of mesenchymal stem cells under an SDF-1α gradient on a microfluidic device
Homing of peripheral stem cells is regulated by one of the most representative homing factors, stromal cell-derived factor 1 alpha (SDF-1α), which specifically binds to the plasma membrane receptor CXCR4 of mesenchymal stem cells (MSCs) in order to initiate the signaling pathways that lead to direct...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590985/ https://www.ncbi.nlm.nih.gov/pubmed/28886159 http://dx.doi.org/10.1371/journal.pone.0184595 |