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Directional migration of mesenchymal stem cells under an SDF-1α gradient on a microfluidic device

Homing of peripheral stem cells is regulated by one of the most representative homing factors, stromal cell-derived factor 1 alpha (SDF-1α), which specifically binds to the plasma membrane receptor CXCR4 of mesenchymal stem cells (MSCs) in order to initiate the signaling pathways that lead to direct...

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Detalles Bibliográficos
Autores principales: Park, Siwan, Jang, Hwanseok, Kim, Byung Soo, Hwang, Changmo, Jeong, Gi Seok, Park, Yongdoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590985/
https://www.ncbi.nlm.nih.gov/pubmed/28886159
http://dx.doi.org/10.1371/journal.pone.0184595