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Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing
Alternative splicing is known to remodel protein-protein interaction networks (“interactomes”), yet large-scale determination of isoform-specific interactions remains challenging. We present a domain-based method to predict the isoform interactome from the reference interactome. First, we construct...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591010/ https://www.ncbi.nlm.nih.gov/pubmed/28846689 http://dx.doi.org/10.1371/journal.pcbi.1005717 |