Experimental Vaccine Induces Th1-driven Immune Responses and Resistance to Neisseria gonorrhoeae Infection in a Murine Model

Female mice were immunized intravaginally with gonococcal outer membrane vesicles (OMV) plus microencapsulated IL-12, and challenged using an established model of genital infection with Neisseria gonorrhoeae. Whereas sham-immunized and control animals cleared the infection in 10–13 days, those immun...

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Detalles Bibliográficos
Autores principales: Liu, Yingru, Hammer, Laura A., Liu, Wensheng, Hobbs, Marcia M., Zielke, Ryszard A., Sikora, Aleksandra E., Jerse, Ann E., Egilmez, Nejat K., Russell, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591041/
https://www.ncbi.nlm.nih.gov/pubmed/28272393
http://dx.doi.org/10.1038/mi.2017.11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591041/
https://www.ncbi.nlm.nih.gov/pubmed/28272393
http://dx.doi.org/10.1038/mi.2017.11

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