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Genome-wide linkage analysis and regional fine mapping identified variants in the RYR3 gene as a novel quantitative trait locus for circulating adiponectin in Chinese population

Adiponectin is adipocyte-secreted cytokine with potent insulin-sensitizing action in peripheral tissues. The heritability of plasma adiponectin is high in Han Chinese population. To identify genetic loci influencing plasma adiponectin levels in Chinese population, we performed a genome-wide linkage...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Cheng, Chiu, Yen-Feng, He, Chih-Tsueng, Sheu, Wayne Huey-Herng, Lin, Ming-Wei, Seto, Todd B., Assimes, Themistocles, Jou, Yuh-Shan, Su, Lynn, Lee, Wei-Jei, Lee, Po-Chu, Tsai, Shu-Huei, Chuang, Lee-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591101/
https://www.ncbi.nlm.nih.gov/pubmed/27858853
http://dx.doi.org/10.1097/MD.0000000000005174