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A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics

BACKGROUND: Initiation of antiretroviral therapy (ART) in early HIV infection demonstrates clinical benefits including enhanced CD4(+) T-lymphocyte recovery and minimization of the latent HIV reservoir. Whether ART intensification with CCR5 blockade provides additional benefits is unknown. TRIAL DES...

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Detalles Bibliográficos
Autores principales: Karris, Maile Y., Umlauf, Anya, Vaida, Florin, Richman, Douglas, Little, Susan, Smith, Davey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591160/
https://www.ncbi.nlm.nih.gov/pubmed/27858912
http://dx.doi.org/10.1097/MD.0000000000005315