Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality

A favorable effect of an inhibitor of the sodium–glucose cotransporter 2 (SGLT2i) on mortality of diabetic patients was recently reported, although mechanisms underlying that effect remained unclear. Here, we examine SGLT2i effects on survival of diabetic mice and assess factors underlying these out...

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Detalles Bibliográficos
Autores principales: Sugizaki, Taichi, Zhu, Shunshun, Guo, Ge, Matsumoto, Akiko, Zhao, Jiabin, Endo, Motoyoshi, Horiguchi, Haruki, Morinaga, Jun, Tian, Zhe, Kadomatsu, Tsuyoshi, Miyata, Keishi, Itoh, Hiroshi, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591191/
https://www.ncbi.nlm.nih.gov/pubmed/28900540
http://dx.doi.org/10.1038/s41514-017-0012-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591191/
https://www.ncbi.nlm.nih.gov/pubmed/28900540
http://dx.doi.org/10.1038/s41514-017-0012-0

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