Treatment of diabetic mice with the SGLT2 inhibitor TA-1887 antagonizes diabetic cachexia and decreases mortality

A favorable effect of an inhibitor of the sodium–glucose cotransporter 2 (SGLT2i) on mortality of diabetic patients was recently reported, although mechanisms underlying that effect remained unclear. Here, we examine SGLT2i effects on survival of diabetic mice and assess factors underlying these out...

Descripción completa

Detalles Bibliográficos
Autores principales: Sugizaki, Taichi, Zhu, Shunshun, Guo, Ge, Matsumoto, Akiko, Zhao, Jiabin, Endo, Motoyoshi, Horiguchi, Haruki, Morinaga, Jun, Tian, Zhe, Kadomatsu, Tsuyoshi, Miyata, Keishi, Itoh, Hiroshi, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591191/
https://www.ncbi.nlm.nih.gov/pubmed/28900540
http://dx.doi.org/10.1038/s41514-017-0012-0

Ejemplares similares

Ejemplares similares