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Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid
The differentiation of resident tissue macrophages from embryonic precursors and that of inflammatory macrophages from bone marrow cells leads to macrophage heterogeneity. Further plasticity is displayed through their ability to be polarized as subtypes M1 and M2 in a cell culture microenvironment....
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591212/ https://www.ncbi.nlm.nih.gov/pubmed/28887514 http://dx.doi.org/10.1038/s41598-017-11496-3 |