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Spinal miRNA-124 regulates synaptopodin and nociception in an animal model of bone cancer pain

Strong breakthrough pain is one of the most disabling symptoms of cancer since it affects up to 90% of cancer patients and is often refractory to treatments. Alteration in gene expression is a known mechanism of cancer pain in which microRNAs (miRNAs), a class of non-coding regulatory RNAs, play a c...

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Detalles Bibliográficos
Autores principales: Elramah, Sara, López-González, María José, Bastide, Matthieu, Dixmérias, Florence, Roca-Lapirot, Olivier, Wielanek-Bachelet, Anne-Cécile, Vital, Anne, Leste-Lasserre, Thierry, Brochard, Alexandre, Landry, Marc, Favereaux, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591226/
https://www.ncbi.nlm.nih.gov/pubmed/28887457
http://dx.doi.org/10.1038/s41598-017-10224-1