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Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy

The mechanisms underpinning the failure of inflammation to resolve in diseased musculoskeletal soft tissues are unknown. Herein, we studied bioactive lipid mediator (LM) profiles of tendon-derived stromal cells isolated from healthy donors and patients with chronic tendinopathy. Interleukin(IL)-1β t...

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Detalles Bibliográficos
Autores principales: Dakin, Stephanie G., Ly, Lucy, Colas, Romain A., Oppermann, Udo, Wheway, Kim, Watkins, Bridget, Dalli, Jesmond, Carr, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591234/
https://www.ncbi.nlm.nih.gov/pubmed/28887458
http://dx.doi.org/10.1038/s41598-017-11188-y