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Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy
The mechanisms underpinning the failure of inflammation to resolve in diseased musculoskeletal soft tissues are unknown. Herein, we studied bioactive lipid mediator (LM) profiles of tendon-derived stromal cells isolated from healthy donors and patients with chronic tendinopathy. Interleukin(IL)-1β t...
Autores principales: | Dakin, Stephanie G., Ly, Lucy, Colas, Romain A., Oppermann, Udo, Wheway, Kim, Watkins, Bridget, Dalli, Jesmond, Carr, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591234/ https://www.ncbi.nlm.nih.gov/pubmed/28887458 http://dx.doi.org/10.1038/s41598-017-11188-y |
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