The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation

Prokaryotic proteins must be deformylated before the removal of their first methionine. Peptide deformylase (PDF) is indispensable and guarantees this mechanism. Recent metagenomics studies revealed new idiosyncratic PDF forms as the most abundant family of viral sequences. Little is known regarding...

Descripción completa

Detalles Bibliográficos
Autores principales: Grzela, Renata, Nusbaum, Julien, Fieulaine, Sonia, Lavecchia, Francesco, Bienvenut, Willy V., Dian, Cyril, Meinnel, Thierry, Giglione, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591237/
https://www.ncbi.nlm.nih.gov/pubmed/28887476
http://dx.doi.org/10.1038/s41598-017-11329-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591237/
https://www.ncbi.nlm.nih.gov/pubmed/28887476
http://dx.doi.org/10.1038/s41598-017-11329-3

Ejemplares similares