The Oxidative State of Cysteine Thiol 144 Regulates the SIRT6 Glucose Homeostat

Control of glucose homeostasis plays a critical role in health and lifespan and its dysregulation contributes to inflammation, cancer and aging. NAD + dependent Sirtuin 6 (SIRT6) is a glucose homeostasis regulator in animals and humans and its regulation at the molecular level is unknown. Here, we r...

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Detalles Bibliográficos
Autores principales: Long, David, Wu, Hanzhi, Tsang, Allen W., Poole, Leslie B., Yoza, Barbara K., Wang, Xianfeng, Vachharajani, Vidula, Furdui, Cristina M., McCall, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591240/
https://www.ncbi.nlm.nih.gov/pubmed/28887543
http://dx.doi.org/10.1038/s41598-017-11388-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591240/
https://www.ncbi.nlm.nih.gov/pubmed/28887543
http://dx.doi.org/10.1038/s41598-017-11388-6

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