Cargando…

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

NaPi-IIb/Slc34a2 is a Na(+)-dependent phosphate transporter that accounts for the majority of active phosphate transport into intestinal epithelial cells. Its abundance is regulated by dietary phosphate, being high during dietary phosphate restriction. Intestinal ablation of NaPi-IIb in mice leads t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Knöpfel, Thomas, Pastor-Arroyo, Eva M., Schnitzbauer, Udo, Kratschmar, Denise V., Odermatt, Alex, Pellegrini, Giovanni, Hernando, Nati, Wagner, Carsten A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591270/ https://www.ncbi.nlm.nih.gov/pubmed/28887454 http://dx.doi.org/10.1038/s41598-017-10390-2

Ejemplares similares

Constitutive depletion of Slc34a2/NaPi-IIb in rats causes perinatal mortality
por: Pastor-Arroyo, Eva Maria, et al.
Publicado: (2021)

Phosphate reabsorption in the kidney: NaPi-IIb or not IIb
por: Burns, David, et al.
Publicado: (2020)

Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis
por: Jönsson, Åsa Lina M., et al.
Publicado: (2022)

The human pathogenic 91del7 mutation in SLC34A1 has no effect in mineral homeostasis in mice
por: Bieri, Cornelia, et al.
Publicado: (2022)

Structural models of the NaPi-II sodium-phosphate cotransporters
por: Fenollar-Ferrer, Cristina, et al.
Publicado: (2018)

High Phosphorus Diet-Induced Changes in NaPi-IIb Phosphate Transporter Expression in the Rat Kidney: DNA Microarray Analysis
por: Suyama, Tatsuya, et al.
Publicado: (2012)

NaPi-IIb Inhibition for Hyperphosphatemia in CKD Hemodialysis Patients
por: Maruyama, Sonomi, et al.
Publicado: (2020)

Regulation of vitamin D metabolizing enzymes in murine renal and extrarenal tissues by dietary phosphate, FGF23, and 1,25(OH)(2)D(3)
por: Kägi, Larissa, et al.
Publicado: (2018)

Differential regulation of the renal sodium-phosphate cotransporters NaPi-IIa, NaPi-IIc, and PiT-2 in dietary potassium deficiency
por: Breusegem, Sophia Y., et al.
Publicado: (2009)

Does the composition of urinary extracellular vesicles reflect the abundance of renal Na(+)/phosphate transporters?
por: Radvanyi, Zsuzsi, et al.
Publicado: (2022)

Targeting NaPi-IIb for Hyperphosphatemia in Chronic Kidney Disease Patients - The Dead End?
por: Apetrii, Mugurel, et al.
Publicado: (2021)

Renal localization and regulation by dietary phosphate of the MCT14 orphan transporter
por: Knöpfel, Thomas, et al.
Publicado: (2017)

Inorganic Phosphate Modulates the Expression of the NaPi-2a Transporter in the trans-Golgi Network and the Interaction with PIST in the Proximal Tubule
por: Lanaspa, Miguel A., et al.
Publicado: (2013)

The role of SLC34A2 in intestinal phosphate absorption and phosphate homeostasis
por: Marks, Joanne
Publicado: (2018)

Sodium-dependent phosphate transporter NaPi2b as a potential predictive marker for targeted therapy of ovarian cancer
por: Nurgalieva, A.K., et al.
Publicado: (2021)

The Influence of Dietary Calcium and Phosphorus Imbalance on Intestinal NaPi-IIb and Calbindin mRNA Expression and Tibia Parameters of Broilers
por: Li, Jianhui, et al.
Publicado: (2012)

Clinical, biochemical, and pathophysiological analysis of SLC34A1 mutations
por: Fearn, Amy, et al.
Publicado: (2018)

Renal Dnase1 expression is regulated by FGF23 but loss of Dnase1 does not alter renal phosphate handling
por: Egli-Spichtig, Daniela, et al.
Publicado: (2021)

Strand selective generation of endo-siRNAs from the Na/phosphate transporter gene Slc34a1 in murine tissues
por: Carlile, Mark, et al.
Publicado: (2009)

Expression of phosphate and calcium transporters and their regulators in parotid glands of mice
por: Moser, Seraina O., et al.
Publicado: (2022)

SLC37A1 and SLC37A2 Are Phosphate-Linked, Glucose-6-Phosphate Antiporters
por: Pan, Chi-Jiunn, et al.
Publicado: (2011)

Sodium-Dependent Phosphate Transporters in Osteoclast Differentiation and Function
por: Albano, Giuseppe, et al.
Publicado: (2015)

Phosphate matters when investigating hypercalcemia: a mutation in SLC34A3 causing HHRH
por: Tang, Andrew R, et al.
Publicado: (2019)

Evidence of an intestinal phosphate transporter alternative to type IIb sodium-dependent phosphate transporter in rats with chronic kidney disease
por: Ichida, Yasuhiro, et al.
Publicado: (2020)

Evaluating pathogenicity of SLC34A3-Ser192Leu, a frequent European missense variant in disorders of renal phosphate wasting
por: Schönauer, Ria, et al.
Publicado: (2019)

Rebmab200, a Humanized Monoclonal Antibody Targeting the Sodium Phosphate Transporter NaPi2b Displays Strong Immune Mediated Cytotoxicity against Cancer: A Novel Reagent for Targeted Antibody Therapy of Cancer
por: dos Santos, Mariana Lopes, et al.
Publicado: (2013)

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells
por: Alesutan, Ioana, et al.
Publicado: (2017)

(Na, Zr) and (Ca, Zr) Phosphate-Molybdates and Phosphate-Tungstates: I–Synthesis, Sintering and Characterization
por: Karaeva, M. E., et al.
Publicado: (2023)

Intact FGF23 predicts serum phosphate improvement after combined nicotinamide and phosphate binder treatment in hemodialysis patients
por: Egli-Spichtig, Daniela, et al.
Publicado: (2023)

(Na, Zr) and (Ca, Zr) Phosphate-Molybdates and Phosphate-Tungstates: II–Radiation Test and Hydrolytic Stability
por: Karaeva, M. E., et al.
Publicado: (2023)

The Effect of Moderate Dietary Protein and Phosphate Restriction on Calcium‐Phosphate Homeostasis in Healthy Older Cats
por: Geddes, R.F., et al.
Publicado: (2016)

Physiological Tradeoffs of Immune Response Differs by Infection Type in Pieris napi
por: Keehnen, Naomi L. P., et al.
Publicado: (2021)

Immunohistochemical evaluation of epithelial ovarian carcinomas identifies three different expression patterns of the MX35 antigen, NaPi2b
por: Levan, Kristina, et al.
Publicado: (2017)

Cellular abundance of sodium phosphate cotransporter SLC20A1/PiT1 and phosphate uptake are controlled post-transcriptionally by ESCRT
por: Zechner, Christoph, et al.
Publicado: (2022)

Distinct functional properties of two electrogenic isoforms of the SLC34 Na‐Pi cotransporter
por: Mizutani, Natsuki, et al.
Publicado: (2019)

Toward a Topology-Based Therapeutic Design of Membrane Proteins: Validation of NaPi2b Topology in Live Ovarian Cancer Cells
por: Bulatova, Leisan, et al.
Publicado: (2022)

The complete mitochondrial genome of the Pieris napi (Lepidoptera: Pieridae) and its phylogenetic implication
por: Yu, Hong, et al.
Publicado: (2020)

Sensory Organ Investment Varies with Body Size and Sex in the Butterfly Pieris napi
por: Moradinour, Zahra, et al.
Publicado: (2021)

The Voltage Dependence of a Cloned Mammalian Renal Type II Na(+)/P(i) Cotransporter (NaP(i)-2)
por: Forster, Ian, et al.
Publicado: (1998)

The sodium-phosphate co-transporter SLC34A2, and pulmonary alveolar microlithiasis: Presentation of an inbred family and a novel truncating mutation in exon 3
por: Vismara, Marco Favio Michele, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_fgr26tbq19791nl862734hbh1r