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Evaluating strategies for reversing CRISPR-Cas9 gene drives

A gene drive biases inheritance of a gene so that it increases in frequency within a population even when the gene confers no fitness benefit. There has been renewed interest in environmental releases of engineered gene drives due to recent proof of principle experiments with the CRISPR-Cas9 system...

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Detalles Bibliográficos
Autores principales: Vella, Michael R., Gunning, Christian E., Lloyd, Alun L., Gould, Fred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591286/
https://www.ncbi.nlm.nih.gov/pubmed/28887462
http://dx.doi.org/10.1038/s41598-017-10633-2