Homogeneity and High Concordance of ALK Translocation in Primary Lung Adenocarcinoma and Paired Lymph Node Metastasis

Translocation of anaplastic lymphoma kinase (ALK) gene is an important determinator for the response to ALK tyrosine kinase inhibitor (TKI) in non-small-cell lung cancer (NSCLC) patients. The existence of genetic heterogeneity will affect the results of molecular testing, especially in biopsy sample...

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Detalles Bibliográficos
Autores principales: Ma, Wei, Guo, Lei, Shan, Ling, Liu, Xiuyun, Lyu, Ning, Ying, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591317/
https://www.ncbi.nlm.nih.gov/pubmed/28887531
http://dx.doi.org/10.1038/s41598-017-11453-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591317/
https://www.ncbi.nlm.nih.gov/pubmed/28887531
http://dx.doi.org/10.1038/s41598-017-11453-0

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