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The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome

Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other inflammatory cytokine production is important in antiviral immune responses. Furthermore, altered TLR7 expression levels are i...

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Detalles Bibliográficos
Autores principales: Petes, Carlene, Odoardi, Natalya, Gee, Katrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591332/
https://www.ncbi.nlm.nih.gov/pubmed/28928743
http://dx.doi.org/10.3389/fimmu.2017.01075