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The Toll for Trafficking: Toll-Like Receptor 7 Delivery to the Endosome
Toll-like receptor (TLR)-7 is an endosomal innate immune sensor capable of detecting single-stranded ribonucleic acid. TLR7-mediated induction of type I interferon and other inflammatory cytokine production is important in antiviral immune responses. Furthermore, altered TLR7 expression levels are i...
Autores principales: | Petes, Carlene, Odoardi, Natalya, Gee, Katrina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591332/ https://www.ncbi.nlm.nih.gov/pubmed/28928743 http://dx.doi.org/10.3389/fimmu.2017.01075 |
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