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Alteration in plasma and striatal levels of d-serine after d-serine administration with or without nicergoline: An in vivo microdialysis study

AIMS: d-Serine (d-Ser), a co-agonist of N-methyl-d-aspartate receptor (NMDAR), is effective for treating schizophrenia. The present study investigated changes in plasma and striatal d-Ser levels in Sprague-Dawley (SD) rats after intraperitoneal d-Ser administration alone or together with nicergoline...

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Detalles Bibliográficos
Autores principales: Onozato, Mayu, Nakazawa, Hiromi, Ishimaru, Katsuyuki, Nagashima, Chihiro, Fukumoto, Minori, Hakariya, Hitomi, Sakamoto, Tatsuya, Ichiba, Hideaki, Fukushima, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591394/
https://www.ncbi.nlm.nih.gov/pubmed/28924620
http://dx.doi.org/10.1016/j.heliyon.2017.e00399