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Dynamics of sodium current mediated early afterdepolarizations

Early afterdepolarizations (EADs) have been attributed to two primary mechanisms: 1) recovery from inactivation of the L-type calcium (Ca) channel and/or 2) spontaneous Ca release, which depolarizes the membrane potential through the electrogenic sodium-calcium exchanger (NCX). The sodium (Na) curre...

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Detalles Bibliográficos
Autores principales: Sato, Daisuke, Clancy, Colleen E., Bers, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591396/
https://www.ncbi.nlm.nih.gov/pubmed/28924617
http://dx.doi.org/10.1016/j.heliyon.2017.e00388