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Effects of Simvastatin Beyond Dyslipidemia: Exploring Its Antinociceptive Action in an Animal Model of Complex Regional Pain Syndrome-Type I

Simvastatin is a lipid-lowering agent that blocks the production of cholesterol through inhibition of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase. In addition, recent evidence has suggested its anti-inflammatory and antinociceptive actions during inflammatory and pain disorders. Herein,...

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Detalles Bibliográficos
Autores principales: Vieira, Graziela, Cavalli, Juliana, Gonçalves, Elaine C. D., Gonçalves, Tainara R., Laurindo, Larissa R., Cola, Maíra, Dutra, Rafael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591456/
https://www.ncbi.nlm.nih.gov/pubmed/28928655
http://dx.doi.org/10.3389/fphar.2017.00584