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Effects of Simvastatin Beyond Dyslipidemia: Exploring Its Antinociceptive Action in an Animal Model of Complex Regional Pain Syndrome-Type I
Simvastatin is a lipid-lowering agent that blocks the production of cholesterol through inhibition of 3-hydroxy-methyl-glutaryl coenzyme A (HMG-CoA) reductase. In addition, recent evidence has suggested its anti-inflammatory and antinociceptive actions during inflammatory and pain disorders. Herein,...
Autores principales: | Vieira, Graziela, Cavalli, Juliana, Gonçalves, Elaine C. D., Gonçalves, Tainara R., Laurindo, Larissa R., Cola, Maíra, Dutra, Rafael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591456/ https://www.ncbi.nlm.nih.gov/pubmed/28928655 http://dx.doi.org/10.3389/fphar.2017.00584 |
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