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Cancer heterogeneity: converting a limitation into a source of biologic information
Analysis of spatial and temporal genetic heterogeneity in human cancers has revealed that somatic cancer evolution in most cancers is not a simple linear process composed of a few sequential steps of mutation acquisitions and clonal expansions. Parallel evolution has been observed in many early huma...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591523/ https://www.ncbi.nlm.nih.gov/pubmed/28886708 http://dx.doi.org/10.1186/s12967-017-1290-9 |