Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

BACKGROUND: The molecular mechanism underlying progressive memory loss in Alzheimer’s disease is poorly understood. Neurogenesis in the adult hippocampus is a dynamic process that continuously changes the dentate gyrus and is important for hippocampal plasticity, learning and memory. However, whethe...

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Detalles Bibliográficos
Autores principales: Hollands, Carolyn, Tobin, Matthew Kyle, Hsu, Michael, Musaraca, Kianna, Yu, Tzong-Shiue, Mishra, Rachana, Kernie, Steven G., Lazarov, Orly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591545/
https://www.ncbi.nlm.nih.gov/pubmed/28886753
http://dx.doi.org/10.1186/s13024-017-0207-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591545/
https://www.ncbi.nlm.nih.gov/pubmed/28886753
http://dx.doi.org/10.1186/s13024-017-0207-7

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