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Depletion of adult neurogenesis exacerbates cognitive deficits in Alzheimer’s disease by compromising hippocampal inhibition

BACKGROUND: The molecular mechanism underlying progressive memory loss in Alzheimer’s disease is poorly understood. Neurogenesis in the adult hippocampus is a dynamic process that continuously changes the dentate gyrus and is important for hippocampal plasticity, learning and memory. However, whethe...

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Detalles Bibliográficos
Autores principales:	Hollands, Carolyn, Tobin, Matthew Kyle, Hsu, Michael, Musaraca, Kianna, Yu, Tzong-Shiue, Mishra, Rachana, Kernie, Steven G., Lazarov, Orly
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591545/ https://www.ncbi.nlm.nih.gov/pubmed/28886753 http://dx.doi.org/10.1186/s13024-017-0207-7

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