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Peroxisome proliferator-activated receptor-gamma: potential molecular therapeutic target for HIV-1-associated brain inflammation

BACKGROUND: Despite the use of combination antiretroviral therapy for the treatment of HIV-1 infection, cognitive impairments remain prevalent due to persistent viral replication and associated brain inflammation. Primary cellular targets of HIV-1 in the brain are macrophages, microglia, and to a ce...

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Detalles Bibliográficos
Autores principales: Omeragic, Amila, Hoque, Md Tozammel, Choi, U-yeong, Bendayan, Reina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591559/
https://www.ncbi.nlm.nih.gov/pubmed/28886715
http://dx.doi.org/10.1186/s12974-017-0957-8