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Gestational Age-Dependent Increase of Survival Motor Neuron Protein in Umbilical Cord-Derived Mesenchymal Stem Cells

BACKGROUND: Spinal muscular atrophy (SMA) is the most common genetic neurological disease leading to infant death. It is caused by loss of survival motor neuron (SMN) 1 gene and subsequent reduction of SMN protein in motor neurons. Because SMN is ubiquitously expressed and functionally linked to gen...

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Detalles Bibliográficos
Autores principales: Iwatani, Sota, Harahap, Nur Imma Fatimah, Nurputra, Dian Kesumapramudya, Tairaku, Shinya, Shono, Akemi, Kurokawa, Daisuke, Yamana, Keiji, Thwin, Khin Kyae Mon, Yoshida, Makiko, Mizobuchi, Masami, Koda, Tsubasa, Fujioka, Kazumichi, Taniguchi-Ikeda, Mariko, Yamada, Hideto, Morioka, Ichiro, Iijima, Kazumoto, Nishio, Hisahide, Nishimura, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591793/
https://www.ncbi.nlm.nih.gov/pubmed/28929094
http://dx.doi.org/10.3389/fped.2017.00194