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MDCO-216 Does Not Induce Adverse Immunostimulation, in Contrast to Its Predecessor ETC-216

PURPOSE: Aim of this study was to demonstrate that MDCO-216 (human recombinant Apolipoprotein A-I Milano) does not induce adverse immunostimulation, in contrast to its predecessor, ETC-216, which was thought to contain host cell proteins (HCPs) that elicited an inflammatory reaction. METHODS: Data w...

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Detalles Bibliográficos
Autores principales: Reijers, Joannes A. A., Kallend, D. G., Malone, K. E., Jukema, J. W., Wijngaard, P. L. J., Burggraaf, J., Moerland, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591804/
https://www.ncbi.nlm.nih.gov/pubmed/28844118
http://dx.doi.org/10.1007/s10557-017-6746-x