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Adenosine Receptor Stimulation Improves Glucocorticoid-Induced Osteoporosis in a Rat Model

Glucocorticoid-induced osteoporosis (GIO) is a secondary cause of bone loss. Bisphosphonates approved for GIO, might induce jaw osteonecrosis; thus additional therapeutics are required. Adenosine receptor agonists are positive regulators of bone remodeling, thus the efficacy of adenosine receptor st...

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Detalles Bibliográficos
Autores principales: Pizzino, Gabriele, Irrera, Natasha, Galfo, Federica, Oteri, Giacomo, Atteritano, Marco, Pallio, Giovanni, Mannino, Federica, D’Amore, Angelica, Pellegrino, Enrica, Aliquò, Federica, Anastasi, Giuseppe P., Cutroneo, Giuseppina, Squadrito, Francesco, Altavilla, Domenica, Bitto, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591884/
https://www.ncbi.nlm.nih.gov/pubmed/28928654
http://dx.doi.org/10.3389/fphar.2017.00558