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Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model

The aim of the study was to investigate the influence of complement component C3 global depletion on the biological structure and function of the aged retina. In vivo morphology (OCT), electrophysiological function (ERG), and the expression of selected oxidative stress-, apoptosis-, and autophagy-re...

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Detalles Bibliográficos
Autores principales: Rogińska, Dorota, Kawa, Miłosz P., Pius-Sadowska, Ewa, Lejkowska, Renata, Łuczkowska, Karolina, Wiszniewska, Barbara, Kaarniranta, Kai, Paterno, Jussi J., Schmidt, Christian A., Machaliński, Bogusław, Machalińska, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591916/
https://www.ncbi.nlm.nih.gov/pubmed/28928904
http://dx.doi.org/10.1155/2017/5306790