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Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model
The aim of the study was to investigate the influence of complement component C3 global depletion on the biological structure and function of the aged retina. In vivo morphology (OCT), electrophysiological function (ERG), and the expression of selected oxidative stress-, apoptosis-, and autophagy-re...
Autores principales: | Rogińska, Dorota, Kawa, Miłosz P., Pius-Sadowska, Ewa, Lejkowska, Renata, Łuczkowska, Karolina, Wiszniewska, Barbara, Kaarniranta, Kai, Paterno, Jussi J., Schmidt, Christian A., Machaliński, Bogusław, Machalińska, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591916/ https://www.ncbi.nlm.nih.gov/pubmed/28928904 http://dx.doi.org/10.1155/2017/5306790 |
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