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Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species

A progressive decline in antioxidant potential and accumulation of reactive oxygen species (ROS) are major causes of pathogenesis of several diseases, including glaucoma. Trabecular meshwork (TM) dysfunction resulting in higher intraocular pressure (IOP) is a hallmark of glaucoma, but its causes are...

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Detalles Bibliográficos
Autores principales: Chhunchha, Bhavana, Singh, Prerna, Stamer, W Daniel, Singh, Dhirendra P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592691/
https://www.ncbi.nlm.nih.gov/pubmed/28904819
http://dx.doi.org/10.1038/cddiscovery.2017.60