Expression of transcription factors in MEN1-associated pancreatic neuroendocrine tumors

MEN1-associated pancreatic neuroendocrine tumors (pNETs) may potentially express distinct hormones, but the mechanism has not been elucidated. Transcription factors such as MafA and Pdx1 have been identified to lead to beta cell differentiation, while Arx and Brn4 to alpha cell differentiation in de...

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Detalles Bibliográficos
Autores principales: Takeda, Yasutaka, Fujita, Yukihiro, Sakai, Kentaro, Abe, Tomoe, Nakamura, Tomonobu, Yanagimachi, Tsuyoshi, Sakagami, Hidemitsu, Honjo, Jun, Abiko, Atsuko, Makino, Yuichi, Haneda, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Insight into Disease Pathogenesis or Mechanism of Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592709/
https://www.ncbi.nlm.nih.gov/pubmed/28924486
http://dx.doi.org/10.1530/EDM-17-0088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592709/
https://www.ncbi.nlm.nih.gov/pubmed/28924486
http://dx.doi.org/10.1530/EDM-17-0088

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