Cas9-mediated excision of Nematostella brachyury disrupts endoderm development, pharynx formation and oral-aboral patterning

The mesoderm is a key novelty in animal evolution, although we understand little of how the mesoderm arose. brachyury, the founding member of the T-box gene family, is a key gene in chordate mesoderm development. However, the brachyury gene was present in the common ancestor of fungi and animals lon...

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Detalles Bibliográficos
Autores principales: Servetnick, Marc D., Steinworth, Bailey, Babonis, Leslie S., Simmons, David, Salinas-Saavedra, Miguel, Martindale, Mark Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592810/
https://www.ncbi.nlm.nih.gov/pubmed/28705897
http://dx.doi.org/10.1242/dev.145839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592810/
https://www.ncbi.nlm.nih.gov/pubmed/28705897
http://dx.doi.org/10.1242/dev.145839

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