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Rho GTPases as therapeutic targets in cancer (Review)

Rho GTPases are key molecular switches controlling the transduction of external signals to cytoplasmic and nuclear effectors. In the last few years, the development of genetic and pharmacological tools has allowed a more precise definition of the specific roles of Rho GTPases in cancer. The aim of t...

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Detalles Bibliográficos
Autores principales: Cardama, G.A., Gonzalez, N., Maggio, J., Menna, P. Lorenzano, Gomez, D.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592879/
https://www.ncbi.nlm.nih.gov/pubmed/28848995
http://dx.doi.org/10.3892/ijo.2017.4093