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A calpain inhibitor protects against fractalkine production in lipopolysaccharide-treated endothelial cells

BACKGROUND: Fractalkine (CX3CL1) is a chemokine with a unique CX3C motif and is produced by endothelial cells stimulated with lipopolysaccharide (LPS), tumor necrosis factor (TNF)-α, interleukin (IL)-1, and interferon-γ. There have been several reports that the caspase/calpain system is activated in...

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Detalles Bibliográficos
Autores principales: Jang, Jaewoong, Yoon, Yoosik, Oh, Dong-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Nephrology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592889/
https://www.ncbi.nlm.nih.gov/pubmed/28904873
http://dx.doi.org/10.23876/j.krcp.2017.36.3.224