Variance component testing for identifying differentially expressed genes in RNA-seq data

RNA sequencing (RNA-Seq) enables the measurement and comparison of gene expression with isoform-level quantification. Differences in the effect of each isoform may make traditional methods, which aggregate isoforms, ineffective. Here, we introduce a variance component-based test that can jointly tes...

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Detalles Bibliográficos
Autores principales: Yang, Sheng, Shao, Fang, Duan, Weiwei, Zhao, Yang, Chen, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592911/
https://www.ncbi.nlm.nih.gov/pubmed/28929020
http://dx.doi.org/10.7717/peerj.3797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592911/
https://www.ncbi.nlm.nih.gov/pubmed/28929020
http://dx.doi.org/10.7717/peerj.3797

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