ASPsiRNA: A Resource of ASP-siRNAs Having Therapeutic Potential for Human Genetic Disorders and Algorithm for Prediction of Their Inhibitory Efficacy

Allele-specific siRNAs (ASP-siRNAs) have emerged as promising therapeutic molecules owing to their selectivity to inhibit the mutant allele or associated single-nucleotide polymorphisms (SNPs) sparing the expression of the wild-type counterpart. Thus, a dedicated bioinformatics platform encompassing...

Descripción completa

Detalles Bibliográficos
Autores principales: Monga, Isha, Qureshi, Abid, Thakur, Nishant, Gupta, Amit Kumar, Kumar, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592921/
https://www.ncbi.nlm.nih.gov/pubmed/28696921
http://dx.doi.org/10.1534/g3.117.044024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592921/
https://www.ncbi.nlm.nih.gov/pubmed/28696921
http://dx.doi.org/10.1534/g3.117.044024

Ejemplares similares