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The SEK-1 p38 MAP Kinase Pathway Modulates Gq Signaling in Caenorhabditis elegans

Gq is a heterotrimeric G protein that is widely expressed in neurons and regulates neuronal activity. To identify pathways regulating neuronal Gq signaling, we performed a forward genetic screen in Caenorhabditis elegans for suppressors of activated Gq. One of the suppressors is an allele of sek-1,...

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Detalles Bibliográficos
Autores principales: Hoyt, Jill M., Wilson, Samuel K., Kasa, Madhuri, Rise, Jeremy S., Topalidou, Irini, Ailion, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592925/
https://www.ncbi.nlm.nih.gov/pubmed/28696924
http://dx.doi.org/10.1534/g3.117.043273