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A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis

The chromosomal passenger complex (CPC) is a key regulator of eukaryotic cell division, consisting of the protein kinase Aurora B/Ipl1 in association with its activator (INCENP/Sli15) and two additional proteins (Survivin/Bir1 and Borealin/Nbl1). Here, we report a genome-wide genetic interaction scr...

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Detalles Bibliográficos
Autores principales: Makrantoni, Vasso, Ciesiolka, Adam, Lawless, Conor, Fernius, Josefin, Marston, Adele, Lydall, David, Stark, Michael J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592945/
https://www.ncbi.nlm.nih.gov/pubmed/28754723
http://dx.doi.org/10.1534/g3.117.300089