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Layer-by-layer nanoparticles co-loading gemcitabine and platinum (IV) prodrugs for synergistic combination therapy of lung cancer

PURPOSE: Cisplatin plus gemcitabine (GEM) is a standard regimen for the first-line treatment of advanced non-small cell lung cancer. The aim of this study was to prepare biocompatible and biodegradable polymeric prodrugs and construct nanoparticles (NPs) with layer-by-layer (LbL) technique. METHODS:...

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Detalles Bibliográficos
Autores principales: Zhang, Rongrong, Ru, Yun, Gao, Yiping, Li, Jinyin, Mao, Shilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592956/
https://www.ncbi.nlm.nih.gov/pubmed/28919713
http://dx.doi.org/10.2147/DDDT.S143047