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Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

Mitochondrial DNA copy number is strictly regulated during development as naive cells differentiate into mature cells to ensure that specific cell types have sufficient copies of mitochondrial DNA to perform their specialised functions. Mitochondrial DNA haplotypes are defined as specific regions of...

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Detalles Bibliográficos
Autores principales: Lee, William T, Sun, Xin, Tsai, Te-Sha, Johnson, Jacqueline L, Gould, Jodee A, Garama, Daniel J, Gough, Daniel J, McKenzie, Matthew, Trounce, Ian A, St. John, Justin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592988/
https://www.ncbi.nlm.nih.gov/pubmed/28900542
http://dx.doi.org/10.1038/cddiscovery.2017.62