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Exceptional durable response to everolimus in a patient with biphenotypic breast cancer harboring an STK11 variant

Metastatic triple-negative breast cancer comprises 12%–17% of breast cancers and carries a poor prognosis relative to other breast cancer subtypes. Treatment options in this disease are largely limited to systemic chemotherapy. A majority of clinical studies assessing efficacy of targeted therapeuti...

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Detalles Bibliográficos
Autores principales: Parachoniak, Christine A., Rankin, Andrew, Gaffney, Bernadette, Hartmaier, Ryan, Spritz, Dan, Erlich, Rachel L., Miller, Vincent A., Morosini, Deborah, Stephens, Phil, Ross, Jeffrey S., Keech, John, Chmielecki, Juliann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593157/
https://www.ncbi.nlm.nih.gov/pubmed/28550065
http://dx.doi.org/10.1101/mcs.a000778